Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656643 | 0.89 | MTOR (0.67) | MTORPIK3CA | |
| SCHEMBL55204 | 0.89 | MTOR (0.69) | MTORPIK3CA | |
| SCHEMBL56205 | 0.88 | PIK3CA (0.64) | MTORPIK3CA | |
| SCHEMBL55412 | 0.87 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL3659399 | 0.85 | MTOR (0.85) | MTORPIK3CA | |
| SCHEMBL54835 | 0.85 | MTOR (0.71) | MTORPIK3CA | |
| SCHEMBL56227 | 0.85 | MTOR (0.67) | MTORPIK3CA | |
| SCHEMBL55309 | 0.82 | PIK3CA (1.00) | MTORPIK3CA | |
| SCHEMBL55159 | 0.82 | MTOR (0.66) | MTORPIK3CA | |
| SCHEMBL56563 | 0.82 | PIK3CA (0.59) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212333-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | Wyeth LLC (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009052145-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | WYETH (US) | 2009-04-23 | — | — | WO | claimed |
| EP-2212333-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | Wyeth LLC (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052145-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | WYETH (US) | 2009-04-23 | — | — | WO | disclosed |