SCHEMBL3713007

SCHEMBL3713007

C#Cc1cc(C#N)ccc1OCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 18/20 0.67
CYP2C9 P11712 1/20 0.44
AKR1B1 P15121 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3951141 0.89 PTGDR2 (0.67) PTGDR2CYP2C9AKR1B1
SCHEMBL1369812 0.81 PTGDR2 (0.47) PTGDR2
SCHEMBL1372016 0.80 PTGDR2 (1.00) PTGDR2CYP2C9
SCHEMBL3716615 0.80 PTGDR2 (0.63) PTGDR2CYP2C9
SCHEMBL1371792 0.79 PTGDR2 (0.68) PTGDR2CYP2C9
SCHEMBL2771927 0.79 PTGDR2 (0.63) PTGDR2AKR1B1
SCHEMBL21313903 0.79 PTGDR2 (0.63) PTGDR2
SCHEMBL21060145 0.79 PTGDR2 (0.59) PTGDR2
SCHEMBL1371244 0.79 PTGDR2 (0.63) PTGDR2AKR1B1
SCHEMBL6071781 0.79 PTGDR2 (0.63) PTGDR2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396295-A1 PHENOXY ACETIC ACID DERIVATIVES Merck Serono S.A. (CH) 2011-12-21 EP disclosed
WO-2010092043-A1 PHENOXY ACETIC ACID DERIVATIVES MERCK SERONO S.A. (CH) 2010-08-19 WO disclosed