Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121400 | 1.00 | MAPT (0.47) | MAPTLMNAMGLLKDM5BKMT2A | |
| SCHEMBL2121394 | 1.00 | MAPT (0.47) | MAPTLMNAMGLLKDM5BKMT2A | |
| SCHEMBL479484 | 0.92 | MAPT (0.49) | MAPTLMNAKMT2AMEN1GAA | |
| SCHEMBL479483 | 0.92 | MAPT (0.49) | MAPTLMNAKMT2AMEN1GAA | |
| SCHEMBL480525 | 0.91 | MAPT (0.44) | MAPTLMNAMGLLKDM5BKMT2A | |
| SCHEMBL3148593 | 0.91 | PTPN1 (0.42) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL480528 | 0.91 | MAPT (0.44) | MAPTLMNAMGLLKDM5BKMT2A | |
| SCHEMBL3148605 | 0.91 | PTPN1 (0.42) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL479564 | 0.91 | HIF1A (0.40) | MAPTLMNAKMT2APLK4CHEK1 | |
| SCHEMBL479562 | 0.91 | HIF1A (0.40) | MAPTLMNAKMT2APLK4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |