Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369159 | 0.85 | GAA (0.44) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL1390521 | 0.84 | MGAM (0.53) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL1390916 | 0.84 | MGAM (0.53) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL370252 | 0.84 | MGAM (0.53) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL370930 | 0.81 | EPHX2 (0.45) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL369868 | 0.81 | KMT2A (0.47) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL369294 | 0.81 | GAA (0.40) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL369498 | 0.81 | EPHX2 (0.59) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL370215 | 0.80 | MGAM (0.53) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL371201 | 0.80 | MGAM (0.53) | GAAMGAMSIMGAM2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |