Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188923 | 0.93 | PIK3CG (0.49) | PIK3CGPIK3CAABL1DYRK1A | |
| SCHEMBL13189027 | 0.93 | PIK3CG (0.50) | PIK3CGPIK3CAABL1DYRK1A | |
| SCHEMBL13188602 | 0.89 | DYRK1A (0.38) | PIK3CGPIK3CAABL1PIK3CDDYRK1A | |
| SCHEMBL13188603 | 0.88 | PIK3CG (0.36) | PIK3CGPIK3CAABL1PIK3CDDYRK1A | |
| SCHEMBL13188683 | 0.88 | PIK3CG (0.36) | PIK3CGPIK3CAABL1PIK3CDDYRK1A | |
| SCHEMBL13188327 | 0.87 | PIK3CG (0.65) | PIK3CGPIK3CAABL1PIK3CD | |
| SCHEMBL13188159 | 0.87 | ABL1 (0.39) | PIK3CGPIK3CAABL1DYRK1A | |
| SCHEMBL13188581 | 0.84 | PIK3CG (0.44) | PIK3CGPIK3CAABL1 | |
| SCHEMBL13188577 | 0.82 | DYRK1A (0.39) | PIK3CGPIK3CAABL1PIK3CDDYRK1A | |
| SCHEMBL13188736 | 0.81 | PIK3CG (0.37) | PIK3CGPIK3CAABL1PIK3CDDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |