Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.82 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.82 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.82 |
| ▸ | CDK9 | P50750 | 8/20 | 0.82 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.82 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.82 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.82 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.82 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.82 |
| ▸ | GSK3A | P49840 | 1/20 | 0.82 |
| ▸ | GSK3B | P49841 | 1/20 | 0.82 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.71 |
| ▸ | CDK1 | P06493 | 6/20 | 0.71 |
| ▸ | CCNK | O75909 | 2/20 | 0.71 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.71 |
| ▸ | CDK4 | P11802 | 2/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.71 |
| ▸ | CCND1 | P24385 | 2/20 | 0.71 |
| ▸ | CDK7 | P50613 | 2/20 | 0.71 |
| ▸ | CCNH | P51946 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718719 | 0.90 | CDK2 (1.00) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL3718729 | 0.90 | CDK2 (1.00) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL7889584 | 0.88 | CDK2 (0.82) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL15372679 | 0.86 | CDK2 (0.78) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL13001908 | 0.86 | CDK2 (0.79) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL3768325 | 0.86 | CDK2 (0.79) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL3768333 | 0.86 | CDK2 (0.79) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL13811270 | 0.86 | CDK2 (0.81) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL15940645 | 0.85 | CDK2 (0.79) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL23683123 | 0.85 | CDK5 (0.82) | CDK2CCNA2CCNA1CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103473-A1 | METHOD OF TREATMENT OF POLYCYSTIC DISEASES AND CHRONIC LYMPHOCYTIC LEUKEMIA | CHU DE BREST (FR) | 2010-09-16 | — | — | WO | disclosed |