Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707845 | 0.94 | LPAR1 (0.46) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3705514 | 0.92 | LPAR1 (0.52) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3709587 | 0.91 | LPAR1 (0.51) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL2338066 | 0.90 | LPAR1 (0.51) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3704851 | 0.87 | LPAR1 (0.42) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3706377 | 0.87 | LPAR1 (0.39) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3717659 | 0.86 | LPAR1 (0.42) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3713550 | 0.86 | LPAR1 (0.50) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3707600 | 0.85 | LPAR1 (0.60) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3707274 | 0.85 | LPAR1 (0.42) | LPAR1LPAR3LPAR2SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |