SCHEMBL3714741

SCHEMBL3714741

C=Cc1ccc(S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 2/20 0.40
MCL1 Q07820 2/20 0.36
TRPA1 O75762 1/20 0.36
GSK3B P49841 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
TP53 P04637 1/20 0.33
CISD1 Q9NZ45 1/20 0.33
TNNI3 P19429 1/20 0.32
TNNT2 P45379 1/20 0.32
TNNC1 P63316 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
TSHR P16473 1/20 0.31
RAD1 O60671 1/20 0.31
P2RY6 Q15077 1/20 0.31
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
GSK3A P49840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17171613 0.84 TDP1 (0.52) TDP1ALDH1A1MCL1TRPA1TP53
SCHEMBL16856772 0.84 TDP1 (0.52) TDP1ALDH1A1MCL1TRPA1ESR1
SCHEMBL30757967 0.84 TDP1 (0.52) TDP1ALDH1A1MCL1TRPA1GSK3B
SCHEMBL1470769 0.84 TDP1 (0.52) TDP1ALDH1A1MCL1TRPA1GSK3B
SCHEMBL11873084 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1GSK3B
Hydrochloric Acid SCHEMBL29128987 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1TP53
SCHEMBL28279718 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1TP53
SCHEMBL11128225 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1ESR1
SCHEMBL11828925 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1TP53
SCHEMBL11128507 0.82 TDP1 (0.50) TDP1ALDH1A1MCL1TRPA1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010135167-A1 COPOLYELECTROLYTE MONOMERS BEARING MULTIPLE ACID GROUPS ARKEMA INC. (US) 2010-11-25 WO disclosed
US-3980713-A FLUORESCENT BRIGHTENERS NIPPON KAYAKU CO., LTD. (JA) 1976-09-14 US disclosed