Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 13/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716507 | 0.89 | PRLHR (0.36) | PRLHRHTR2CHTR2BHTR2ASIGMAR1 | |
| SCHEMBL3713570 | 0.87 | PRLHR (0.35) | PRLHRHTR2CHTR2BHTR2ATNKS | |
| SCHEMBL3716369 | 0.83 | PRLHR (0.39) | PRLHRHTR2CHTR2B | |
| SCHEMBL3715407 | 0.80 | PRLHR (0.35) | PRLHRHTR2CHTR2BHTR2ATNKS | |
| SCHEMBL3717594 | 0.77 | HTR2C (0.37) | PRLHRHTR2CHTR2B | |
| SCHEMBL3716574 | 0.76 | PRLHR (0.47) | PRLHR | |
| SCHEMBL3724225 | 0.75 | HTR2C (0.36) | PRLHRHTR2CHTR2B | |
| SCHEMBL436071 | 0.74 | PRLHR (0.62) | PRLHR | |
| SCHEMBL3801713 | 0.73 | PRLHR (0.46) | PRLHR | |
| SCHEMBL3721666 | 0.73 | PRLHR (0.49) | PRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |