SCHEMBL3715422

SCHEMBL3715422

COn1c(NCC(C)Cc2ccc(Cl)cc2)nc2c(c1=O)CNCC2

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3721666 1.00 PRLHR (0.49) PRLHR
SCHEMBL3716509 0.85 PRLHR (0.51) PRLHR
SCHEMBL3713572 0.84 PRLHR (0.49) PRLHR
SCHEMBL436071 0.81 PRLHR (0.62) PRLHR
SCHEMBL434454 0.79 PRLHR (0.64) PRLHR
SCHEMBL434425 0.78 PRLHR (0.64) PRLHR
SCHEMBL436152 0.78 PRLHR (0.64) PRLHR
SCHEMBL436151 0.78 PRLHR (0.64) PRLHR
SCHEMBL3716578 0.77 PRLHR (0.61) PRLHR
SCHEMBL434436 0.76 PRLHR (0.41) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed