Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 18/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 16/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709194 | 1.00 | UGCG (0.69) | UGCGCYP3A4HDAC8 | |
| SCHEMBL13260997 | 0.89 | UGCG (0.68) | UGCGCYP3A4 | |
| SCHEMBL13260962 | 0.85 | UGCG (0.83) | UGCGCYP3A4 | |
| SCHEMBL13260370 | 0.84 | UGCG (0.61) | UGCGCYP3A4 | |
| SCHEMBL13260361 | 0.84 | UGCG (0.63) | UGCGCYP3A4HDAC8 | |
| SCHEMBL13260983 | 0.83 | UGCG (0.63) | UGCGCYP3A4HDAC8 | |
| SCHEMBL3805632 | 0.82 | UGCG (0.55) | UGCGCYP3A4 | |
| SCHEMBL21570377 | 0.82 | UGCG (1.00) | UGCGCYP3A4 | |
| SCHEMBL13260130 | 0.82 | UGCG (1.00) | UGCGCYP3A4 | |
| SCHEMBL13260138 | 0.82 | UGCG (1.00) | UGCGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091164-A1 | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |