Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 12/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716221 | 0.97 | HTR2A (0.51) | RAB9ANPC1PKMHTR2AAPP | |
| SCHEMBL3714256 | 0.91 | HTR2A (0.55) | RAB9ANPC1PKMHTR2AAPP | |
| SCHEMBL3716938 | 0.88 | HTR2A (0.59) | RAB9ANPC1PKMHTR2AAPP | |
| SCHEMBL13191493 | 0.88 | HTR2A (0.55) | RAB9ANPC1PKMHTR2AOPRM1 | |
| SCHEMBL3716396 | 0.85 | HTR2A (0.63) | HTR2AOPRM1ABCB11CYP1A2ADRB2 | |
| SCHEMBL3722889 | 0.85 | HTR2A (0.59) | RAB9ANPC1PKMHTR2AAPP | |
| SCHEMBL3723852 | 0.83 | HTR2A (0.70) | HTR2AOPRM1ABCB11CYP1A2ADRB2 | |
| SCHEMBL3719838 | 0.79 | HTR2A (0.59) | HTR2AOPRM1ABCB11CYP1A2ADRB2 | |
| SCHEMBL3716523 | 0.79 | HTR2A (0.59) | HTR2AOPRM1ABCB11CYP1A2ADRB2 | |
| SCHEMBL13191529 | 0.79 | HTR2A (0.57) | HTR2AOPRM1ABCB11CYP1A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |