Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725457 | 0.91 | PTGDR2 (0.50) | PTGDR2AKR1B1 | |
| SCHEMBL1467686 | 0.89 | PTGDR2 (0.73) | PTGDR2 | |
| SCHEMBL1465905 | 0.85 | PTGDR2 (0.58) | PTGDR2AKR1B1 | |
| SCHEMBL1466415 | 0.84 | PTGDR2 (0.81) | PTGDR2AKR1B1 | |
| SCHEMBL3716361 | 0.84 | PTGDR2 (0.53) | PTGDR2AKR1B1 | |
| SCHEMBL1465689 | 0.80 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL1465410 | 0.79 | PTGDR2 (0.51) | PTGDR2AKR1B1 | |
| SCHEMBL1467633 | 0.79 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL1466879 | 0.78 | PTGDR2 (0.57) | PTGDR2AKR1B1 | |
| SCHEMBL1465630 | 0.77 | PTGDR2 (0.48) | PTGDR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | claimed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |