SCHEMBL3716893

SCHEMBL3716893

CCN(c1ccc(C(F)(F)F)cc1)c1nc2c(c(=O)n1OC)CN(C(=O)c1ccc(C#N)cc1)CC2

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3715416 0.93 PRLHR (0.69) PRLHR
SCHEMBL3713145 0.88 PRLHR (0.65) PRLHR
SCHEMBL3717004 0.84 PRLHR (0.68) PRLHR
SCHEMBL3716895 0.83 PRLHR (0.68) PRLHR
SCHEMBL3717897 0.83 PRLHR (0.45) PRLHR
SCHEMBL3720692 0.83 PRLHR (0.66) PRLHR
Hydrochloric Acid SCHEMBL3717997 0.82 PRLHR (0.71) PRLHR
SCHEMBL3723095 0.82 PRLHR (0.56) PRLHR
SCHEMBL3716958 0.81 PRLHR (0.66) PRLHR
SCHEMBL3716885 0.81 PRLHR (0.66) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed