Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2505249 | 1.00 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL2495375 | 1.00 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL2497964 | 0.90 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL2499789 | 0.90 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL2504455 | 0.89 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL2506255 | 0.89 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL2503482 | 0.87 | FFAR1 (0.72) | FFAR1 | |
| SCHEMBL2506472 | 0.87 | FFAR1 (0.72) | FFAR1 | |
| SCHEMBL2502920 | 0.86 | FFAR1 (0.79) | FFAR1 | |
| SCHEMBL2502205 | 0.86 | FFAR1 (0.79) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205548-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | Amgen, Inc (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009048527-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | AMGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |