Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204135 | 1.00 | TSHR (0.72) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL28204149 | 0.98 | TSHR (0.69) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL372784 | 0.97 | TSHR (0.77) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL1014196 | 0.95 | TSHR (0.74) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL8776516 | 0.94 | TSHR (0.67) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL5690541 | 0.94 | TSHR (0.67) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL28230255 | 0.94 | TSHR (0.72) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL28224640 | 0.93 | TSHR (0.66) | TSHRFFAR1FFAR4GPR84THRB | |
| Phosphoric Acid SCHEMBL28232077 | 0.92 | TSHR (0.61) | TSHRFFAR1FFAR4GPR84THRB | |
| SCHEMBL28230256 | 0.92 | TSHR (0.69) | TSHRFFAR1FFAR4GPR84THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112831-A1 | LIQUID CRYSTAL ELASTOMER BEADS | UNIVERSITY OF YORK (GB) | 2010-10-07 | — | — | WO | disclosed |