Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 12/20 | 0.76 |
| ▸ | USP47 | Q96K76 | 3/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722833 | 0.88 | USP7 (0.76) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3716355 | 0.88 | USP7 (0.79) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3722954 | 0.85 | USP7 (0.74) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3712935 | 0.85 | USP7 (0.74) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3717157 | 0.83 | USP7 (0.69) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3712487 | 0.83 | USP7 (0.78) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL3717383 | 0.82 | USP7 (1.00) | USP7USP47PADI4MAPTNPSR1 | |
| SCHEMBL2680950 | 0.79 | USP7 (0.66) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL2680694 | 0.78 | USP7 (0.80) | USP7USP47IDO1PADI4TSHR | |
| SCHEMBL2680726 | 0.77 | USP7 (1.00) | USP7USP47IDO1PADI4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |