SCHEMBL3717242

SCHEMBL3717242

CCN1C2CC(OC(=O)C(CO)c3ccccc3)CC1C1OC12.COS(=O)(=O)O

nearest known ligand 0.70

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 4/20 0.70
CHRM3 known ✓ P20309 2/20 0.70
CHRM4 P08173 3/20 0.70
TSHR P16473 3/20 0.70
CHRM2 P08172 3/20 0.70
LMNA P02545 2/20 0.70
CHRM5 P08912 2/20 0.70
HIF1A Q16665 2/20 0.70
CYP1A2 P05177 1/20 0.70
NFKB1 P19838 1/20 0.70
BLM P54132 3/20 0.69
KMT2A Q03164 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
MEN1 O00255 1/20 0.69
ALDH1A1 P00352 1/20 0.68
TP53 P04637 1/20 0.68
MAPT P10636 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
HSD17B10 Q99714 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183762 0.93 CHRM1 (0.81) CHRM1CHRM4TSHRCHRM2LMNA
Hydrochloric Acid SCHEMBL1724312 0.92 KMT2A (0.81) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL892533 0.91 CHRM4 (0.85) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL892536 0.91 CHRM4 (0.85) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL892535 0.91 CHRM4 (0.85) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL31064233 0.86 CHRM4 (0.91) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL22163750 0.86 CHRM4 (0.91) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL22163749 0.86 CHRM4 (0.91) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL3717240 0.85 CHRM4 (0.85) CHRM1CHRM4TSHRCHRM2LMNA
Scopolamine SCHEMBL28927548 0.83 CHRM1 (0.95) CHRM1CHRM4TSHRCHRM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3849347-A1 LIPOPHILIC ACTIVE AGENT INFUSED TOBACCO LEAVES AND/OR TOBACCO MATERIALS AND METHODS OF USE THEREOF Poviva Corp. (US) 2021-07-21 EP disclosed
WO-2020056344-A1 LIPOPHILIC ACTIVE AGENT INFUSED TOBACCO LEAVES AND/OR TOBACCO MATERIALS AND METHODS OF USE THEREOF POVIVA TEA, LLC (US) 2020-03-19 WO disclosed
WO-2010136219-A1 ENTERIC COATING HEXAL AKTIENGESELLSCHAFT (DE) 2010-12-02 WO disclosed
EP-2034953-A2 ORALLY DISINTEGRATING LAYERED COMPOSITIONS Capricorn Pharma, Inc. (US) 2009-03-18 EP disclosed
WO-2008002529-A2 ORALLY DISINTEGRATING LAYERED COMPOSITIONS CAPRICORN PHARMA, INC. (US) 2008-01-03 WO disclosed
WO-2007062262-A2 GELATINOUS MEDICAMENT FORMULATION AND METHOD OF ADMINISTRATION BRAGINSKY PHILIP Y (US) 2007-05-31 WO disclosed
WO-2004050677-A1 NOVEL CHEMICAL COMPUNDS AND THEIR USE BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-06-17 WO disclosed
WO-2003040104-A1 DIMERIC PHARMACEUTICAL COMPOUNDS AND THEIR USE BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2003-05-15 WO disclosed