Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119646 | 1.00 | MAPT (0.46) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2569915 | 1.00 | MAPT (0.46) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2121405 | 0.92 | MAPT (0.46) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2121402 | 0.92 | MAPT (0.46) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3713292 | 0.92 | MAPT (0.46) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL480525 | 0.92 | MAPT (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL480528 | 0.92 | MAPT (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL479483 | 0.91 | MAPT (0.49) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL479484 | 0.91 | MAPT (0.49) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3161925 | 0.91 | MAPT (0.48) | MAPTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |