Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721180 | 0.92 | PARP10 (0.50) | PARP10PARP15PDK2HPGD | |
| SCHEMBL23484635 | 0.86 | PARP10 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL1391139 | 0.80 | PARP15 (0.44) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL22817029 | 0.80 | PARP10 (0.49) | PARP10PARP15PARP2PDK2HPGD | |
| SCHEMBL14985947 | 0.79 | PPARA (0.37) | ACACBHPGD | |
| SCHEMBL19951551 | 0.79 | PARP15 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL3720859 | 0.79 | PARP10 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL15985640 | 0.79 | PARP15 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL29993061 | 0.79 | PARP15 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL15969380 | 0.78 | PARP10 (0.50) | PARP10PARP15PARP2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |