SCHEMBL3717828

SCHEMBL3717828

COn1c(NCCc2ccc(Cl)cc2)nc2c(c1=O)CN(C(=O)OC(C)(C)C)CC2

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716857 0.95 PRLHR (0.62) PRLHR
SCHEMBL3716374 0.92 PRLHR (0.53) PRLHR
SCHEMBL436052 0.91 PRLHR (0.76) PRLHR
SCHEMBL3717900 0.89 PRLHR (0.54) PRLHR
SCHEMBL3716578 0.88 PRLHR (0.61) PRLHR
SCHEMBL3716391 0.87 PRLHR (0.53) PRLHR
SCHEMBL3719911 0.85 PRLHR (0.60) PRLHR
SCHEMBL3720145 0.84 PRLHR (0.71) PRLHR
SCHEMBL3715452 0.83 PRLHR (0.78) PRLHR
SCHEMBL468942 0.83 PRLHR (0.63) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed