Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717892 | 1.00 | CXCR2 (0.48) | CXCR2CXCR1CCR6 | |
| SCHEMBL13075725 | 0.88 | CXCR2 (0.51) | CXCR2CXCR1CCR6 | |
| SCHEMBL3719173 | 0.85 | CXCR2 (0.57) | CXCR2CXCR1CCR6 | |
| SCHEMBL3719169 | 0.85 | CXCR2 (0.57) | CXCR2CXCR1CCR6 | |
| SCHEMBL248014 | 0.77 | CXCR2 (0.57) | CXCR2CXCR1CCR6 | |
| SCHEMBL3790926 | 0.76 | CXCR2 (0.51) | CXCR2CXCR1CCR6 | |
| SCHEMBL3790925 | 0.76 | CXCR2 (0.51) | CXCR2CXCR1CCR6 | |
| SCHEMBL248194 | 0.75 | CXCR2 (0.57) | CXCR2CXCR1CCR6 | |
| SCHEMBL3712846 | 0.74 | CXCR2 (0.50) | CXCR2CXCR1CCR6 | |
| SCHEMBL3712842 | 0.74 | CXCR2 (0.50) | CXCR2CXCR1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |