Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049300 | 0.93 | PRKDC (0.55) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3717450 | 0.88 | PRKDC (0.58) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3718172 | 0.87 | PRKDC (0.68) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3718691 | 0.86 | PRKDC (0.67) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3723185 | 0.86 | PRKDC (0.66) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL13049313 | 0.86 | PRKDC (0.66) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3721652 | 0.84 | PRKDC (0.63) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3718124 | 0.84 | PRKDC (0.63) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3717396 | 0.83 | PRKDC (0.61) | PRKDCPIK3CAPIK3CBPIK3CDMTOR | |
| SCHEMBL3719111 | 0.83 | PRKDC (0.61) | PRKDCPIK3CAPIK3CBPIK3CDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136778-A1 | DIBENZOTHIOPHENE DERIVATIVES AS DNA- PK INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2010-12-02 | — | — | WO | disclosed |