Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723717 | 0.91 | PTGDR2 (0.72) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3714601 | 0.89 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRALDH1A1LMNA | |
| SCHEMBL1467917 | 0.87 | PTGDR2 (0.60) | PTGDR2PTGDRPTGIRALDH1A1LMNA | |
| SCHEMBL1465689 | 0.85 | PTGDR2 (0.61) | PTGDR2PTGDRPTGIRALDH1A1LMNA | |
| SCHEMBL1467546 | 0.85 | PTGDR2 (0.84) | PTGDR2PTGDRPTGIR | |
| SCHEMBL3718283 | 0.84 | PTGDR2 (0.60) | PTGDR2PTGDRPTGIRALDH1A1LMNA | |
| SCHEMBL1465975 | 0.81 | PTGDR2 (0.82) | PTGDR2 | |
| SCHEMBL3715473 | 0.81 | PTGDR2 (0.63) | PTGDR2PTGDRPTGIR | |
| SCHEMBL1466212 | 0.81 | PTGDR2 (0.84) | PTGDR2PTGDRPTGIRALDH1A1LMNA | |
| SCHEMBL3724417 | 0.81 | PTGDR2 (0.61) | PTGDR2PTGDRPTGIRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |