Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.37 |
| ▸ | PPARD | Q03181 | 13/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 16/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707972 | 0.81 | — | — | |
| SCHEMBL13048306 | 0.79 | PPARD (0.38) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10008447 | 0.79 | PPARD (0.38) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL1707822 | 0.75 | PPARG (0.44) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10010131 | 0.74 | FFAR1 (0.45) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10009300 | 0.74 | PPARD (0.39) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10011110 | 0.73 | FFAR1 (0.48) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10009234 | 0.73 | FFAR1 (0.48) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL10011831 | 0.73 | FFAR1 (0.48) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL1708004 | 0.73 | KCNK3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |