Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075056 | 0.88 | KDM4E (0.45) | HTTCA1CA2MIFTSHR | |
| SCHEMBL24517876 | 0.83 | CA1 (0.50) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL29847021 | 0.83 | CA1 (0.50) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL25401731 | 0.81 | MIF (0.51) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL24518112 | 0.81 | CA1 (0.43) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL24518312 | 0.80 | CA1 (0.58) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL25398334 | 0.79 | CA1 (0.43) | HTTCA1CA2MIFTSHR | |
| SCHEMBL25399156 | 0.78 | MAPT (0.42) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL24517882 | 0.78 | MIF (0.56) | CA1CA2MIFTSHRL3MBTL1 | |
| SCHEMBL24518005 | 0.77 | CA1 (0.43) | CA1CA2MIFTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132547-A2 | OXAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132547-A2 | OXAZA HETEROCYCLIC COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2010-11-18 | — | — | WO | disclosed |