Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 16/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720701 | 0.90 | PRLHR (0.42) | PRLHRHTR2CHTR2BEGLN1 | |
| SCHEMBL3713567 | 0.88 | PRLHR (0.49) | PRLHRHTR2CHTR2B | |
| SCHEMBL434533 | 0.84 | PRLHR (0.58) | PRLHR | |
| SCHEMBL15226157 | 0.84 | PRLHR (0.58) | PRLHR | |
| SCHEMBL3724228 | 0.83 | PRLHR (0.48) | PRLHRHTR2CHTR2B | |
| SCHEMBL3714704 | 0.81 | HTR2C (0.40) | PRLHRHTR2CHTR2BEGLN1HTR2A | |
| SCHEMBL3714279 | 0.79 | PRLHR (0.52) | PRLHR | |
| SCHEMBL3716376 | 0.78 | PRLHR (0.44) | PRLHR | |
| SCHEMBL3723937 | 0.78 | PRLHR (0.42) | PRLHRHTR2CHTR2BEGLN1 | |
| SCHEMBL3719987 | 0.77 | PRLHR (0.39) | PRLHRHTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |