Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 14/20 | 0.47 |
| ▸ | ACACA | Q13085 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723775 | 0.92 | ACACB (0.46) | HTTACACBACACA | |
| SCHEMBL3724567 | 0.88 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL13076364 | 0.88 | ACACB (0.50) | ACACBACACAHCRTR1TDP1 | |
| SCHEMBL3717678 | 0.88 | HTT (0.50) | HTTSMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL3727673 | 0.88 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3727054 | 0.88 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL3726077 | 0.87 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL3727572 | 0.87 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3716839 | 0.86 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL13077051 | 0.86 | ACACB (0.47) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |