Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737283 | 0.98 | NPC1 (0.41) | NPC1HPGDNAAA | |
| SCHEMBL1131773 | 0.81 | NPC1 (0.40) | NPC1 | |
| SCHEMBL29957214 | 0.81 | NPC1 (0.40) | NPC1 | |
| SCHEMBL19124722 | 0.80 | NPC1 (0.42) | NPC1HPGD | |
| SCHEMBL25512525 | 0.79 | SLC6A2 (0.30) | — | |
| SCHEMBL8598726 | 0.78 | — | — | |
| SCHEMBL10357183 | 0.78 | NPC1 (0.61) | NPC1HPGDNAAA | |
| SCHEMBL6377426 | 0.78 | NPC1 (0.61) | NPC1HPGDNAAA | |
| SCHEMBL6376493 | 0.78 | NPC1 (0.61) | NPC1HPGDNAAA | |
| SCHEMBL6383859 | 0.78 | NPC1 (0.61) | NPC1HPGDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141173-A1 | TERPOLYMERS CONTAINING LACTIDE AND GLYCOLIDE | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2010-12-09 | — | — | WO | disclosed |