Propionic Acid

Propionic Acid

SCHEMBL3721083

C1COC1.CCC(=O)O.CNC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.53
HTT P42858 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
GLA P06280 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL144757 0.84 FFAR3 (0.53) FFAR3HTTHDAC3HDAC1HDAC2
Propionic Acid SCHEMBL28314256 0.83
Propionic Acid SCHEMBL626476 0.83
Propionic Acid SCHEMBL28697457 0.83 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL28697459 0.83 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Tetrahydrofuran SCHEMBL27415023 0.81 FFAR3 (0.56) FFAR3HTTHDAC3HDAC1HDAC2
Propionic Acid SCHEMBL28145772 0.81 FFAR3 (0.56) FFAR3HTTHDAC3HDAC1HDAC2
Dioxane SCHEMBL10975415 0.80 FFAR3 (0.62) FFAR3HTTHDAC3HDAC1HDAC2
Propionic Acid SCHEMBL146710 0.80 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL145480 0.80 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010136104-A2 ANTI-DANDRUFF AGENTS MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed