Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.86 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.86 |
| ▸ | IGF1R | P08069 | 9/20 | 0.56 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716630 | 0.93 | CDK19 (0.87) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3724787 | 0.90 | CDK19 (0.81) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3766684 | 0.89 | CDK19 (0.82) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3771405 | 0.89 | CDK19 (0.80) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3716738 | 0.88 | CDK19 (0.81) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3767668 | 0.88 | CDK19 (0.81) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3719823 | 0.88 | CDK19 (0.80) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3768992 | 0.87 | CDK19 (0.79) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3764976 | 0.85 | CDK19 (0.76) | CDK19ALKIGF1RINSREGFR | |
| SCHEMBL3756611 | 0.84 | CDK19 (0.73) | CDK19ALKIGF1RINSREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138576-A1 | PYRIMIDINE INHIBITORS OF KINASE ACTIVITY | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | claimed |
| WO-2010138576-A1 | PYRIMIDINE INHIBITORS OF KINASE ACTIVITY | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |