Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14684014 | 0.80 | GSK3B (0.52) | GSK3BPTPN1HDAC1HDAC6 | |
| SCHEMBL691592 | 0.80 | GSK3B (0.52) | GSK3BPTPN1 | |
| SCHEMBL7997993 | 0.80 | HDAC1 (0.50) | GSK3BPTPN1HDAC1HDAC6 | |
| SCHEMBL10588648 | 0.79 | GSK3B (0.42) | GSK3BPTPN1HDAC1HDAC6 | |
| SCHEMBL934394 | 0.77 | GSK3B (0.55) | GSK3BPTPN1 | |
| SCHEMBL12436553 | 0.75 | GSK3B (0.58) | GSK3BPTPN1 | |
| Bromide SCHEMBL6118518 | 0.75 | GSK3B (0.53) | GSK3BPTPN1 | |
| SCHEMBL18397227 | 0.75 | GSK3B (0.52) | GSK3BPTPN1 | |
| SCHEMBL19434282 | 0.75 | GSK3B (0.42) | GSK3BPTPN1 | |
| SCHEMBL7506719 | 0.74 | HCAR2 (0.52) | GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127152-A2 | COMPOUNDS AND COMPOSITIONS AS MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 INHIBITORS | IRM LLC (BM) | 2010-11-04 | — | — | WO | disclosed |