Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191236 | 0.93 | BDKRB1 (0.45) | BDKRB1EPHX2P2RX7F10CNR1 | |
| SCHEMBL13191233 | 0.92 | BDKRB1 (0.44) | BDKRB1EPHX2P2RX7F10HPGDS | |
| SCHEMBL3728513 | 0.92 | BDKRB1 (0.44) | BDKRB1EPHX2P2RX7F10CNR1 | |
| SCHEMBL13191723 | 0.92 | BDKRB1 (0.52) | BDKRB1EPHX2P2RX7F10HPGDS | |
| SCHEMBL13191705 | 0.92 | BDKRB1 (0.44) | BDKRB1EPHX2P2RX7F10HPGDS | |
| SCHEMBL13191721 | 0.91 | BDKRB1 (0.43) | BDKRB1EPHX2P2RX7F10HPGDS | |
| SCHEMBL13191582 | 0.91 | BDKRB1 (0.44) | BDKRB1EPHX2P2RX7F10HPGDS | |
| SCHEMBL13191635 | 0.90 | BDKRB1 (0.40) | BDKRB1CNR1PPARG | |
| SCHEMBL13191622 | 0.90 | EPHX2 (0.47) | BDKRB1EPHX2P2RX7F10PPARG | |
| SCHEMBL13191243 | 0.89 | F10 (0.44) | BDKRB1EPHX2P2RX7F10HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |