⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379611 | 0.58 | — | — | |
| Bicarbonate SCHEMBL28204396 | 0.52 | — | — | |
| Bicarbonate SCHEMBL28104047 | 0.52 | — | — | |
| Bicarbonate SCHEMBL27582976 | 0.48 | — | — | |
| Calcium Chloride SCHEMBL28049911 | 0.47 | — | — | |
| Bicarbonate SCHEMBL28267791 | 0.45 | — | — | |
| Bicarbonate SCHEMBL28421564 | 0.45 | — | — | |
| Bicarbonate SCHEMBL28340624 | 0.45 | — | — | |
| SCHEMBL31481251 | 0.45 | MEN1 (0.36) | — | |
| Bicarbonate SCHEMBL6811967 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222675-A1 | 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE | Genentech, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009089042-A1 | PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009085983-A1 | 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE | GENENTECH, INC. (US) | 2009-07-09 | — | — | WO | disclosed |