Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 14/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716509 | 0.88 | PRLHR (0.51) | PRLHRHTR2CTP53MAPT | |
| SCHEMBL3713567 | 0.86 | PRLHR (0.49) | PRLHRHTR2C | |
| SCHEMBL3713572 | 0.83 | PRLHR (0.49) | PRLHRHTR2C | |
| SCHEMBL3724228 | 0.80 | PRLHR (0.48) | PRLHRHTR2C | |
| SCHEMBL434459 | 0.80 | PRLHR (0.58) | PRLHR | |
| SCHEMBL434460 | 0.78 | PRLHR (0.55) | PRLHRVCPTP53MAPT | |
| SCHEMBL3717900 | 0.78 | PRLHR (0.54) | PRLHR | |
| SCHEMBL3720701 | 0.77 | PRLHR (0.42) | PRLHRHTR2C | |
| SCHEMBL3716879 | 0.76 | PRLHR (0.73) | PRLHR | |
| SCHEMBL3716577 | 0.75 | GSK3B (0.37) | PRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137738-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-12-02 | — | — | WO | disclosed |