Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205597 | 0.85 | AR (0.60) | ARPGR | |
| SCHEMBL19649433 | 0.84 | PDK2 (0.46) | PDK2THRATHRBPTPN7DUSP3 | |
| SCHEMBL32689475 | 0.79 | AR (0.54) | ARPGR | |
| SCHEMBL12778374 | 0.78 | PDK2 (0.43) | PDK2THRATHRBPTPN7DUSP3 | |
| SCHEMBL27336912 | 0.76 | PPARG (0.54) | PDK2THRATHRBPTPN7DUSP3 | |
| SCHEMBL26155371 | 0.76 | ACACB (0.46) | THRATHRB | |
| SCHEMBL10352007 | 0.76 | MAPT (0.48) | PDK2THRATHRBPTPN7DUSP3 | |
| SCHEMBL3718454 | 0.76 | PDK2 (0.43) | PDK2THRATHRBPTPN7DUSP3 | |
| SCHEMBL10187263 | 0.74 | PTGS1 (0.42) | — | |
| SCHEMBL14619305 | 0.74 | AR (0.55) | ARTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081149-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-07-15 | — | — | WO | disclosed |