Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 13/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486021 | 0.91 | F2R (0.64) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL1580636 | 0.87 | F2R (0.60) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL1581192 | 0.87 | F2R (0.77) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL1580503 | 0.87 | F2R (0.59) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL3725314 | 0.87 | F2R (0.47) | F2R | |
| SCHEMBL3793420 | 0.85 | F2R (0.45) | F2RALDH1A1 | |
| SCHEMBL1580496 | 0.85 | F2R (0.58) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL1056124 | 0.84 | F2R (0.54) | F2RRAB9ANPC1MAPTSTAT1 | |
| SCHEMBL3801687 | 0.83 | F2R (0.43) | F2R | |
| SCHEMBL3802456 | 0.83 | F2R (0.49) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136138-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |