⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319228 | 0.97 | PTGS1 (0.36) | — | |
| SCHEMBL5173003 | 0.85 | APP (0.42) | — | |
| SCHEMBL16685221 | 0.83 | APP (0.41) | — | |
| SCHEMBL329794 | 0.78 | — | — | |
| SCHEMBL7520174 | 0.77 | PTGS1 (0.32) | — | |
| SCHEMBL5026578 | 0.76 | — | — | |
| Fluoride SCHEMBL14840306 | 0.76 | PTGS1 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL18008481 | 0.76 | PTGS1 (0.39) | — | |
| Iodide SCHEMBL27949561 | 0.76 | PTGS1 (0.39) | — | |
| Bromide SCHEMBL28075718 | 0.76 | PTGS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254545-B | The aqueous polymer dispersion that can be obtained by the emulsion polymerization that free radical in the presence of lignosulphonates causes | 巴斯夫欧洲公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105518038-A | Solid polymer composition obtained by polymerization of an acid group-containing monomer in the presence of a polyether compound | BASF SE | 2016-04-20 | — | — | CN | claimed |
| CN-102939310-B | Multistage preparation of aqueous polymer dispersions for producing composite films | BASF SE | 2015-04-15 | — | — | CN | claimed |
| CN-104254545-A | Aqueous polymer dispersion obtainable by free-radically initiated emulsion polymerization in the presence of lignosulfonate | BASF SE | 2014-12-31 | — | — | CN | claimed |
| US-20240156766-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-20240139137-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. | 2024-05-02 | — | — | US | disclosed |
| EP-4274561-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | Quadriga Biosciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230348631-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-116847855-A | Pharmaceutical composition of chemotherapeutic agents based on beta-substituted beta-amino acid derivatives | 夸德里加生物科学公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022147743-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022148456-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| US-20210379000-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2021-12-09 | — | — | US | disclosed |
| CN-1086738-C | Method for producing alpha-hydroxy acid using microorganism, and novel microorganism | NIPPON SODA CO (JP) | 2002-06-26 | — | — | CN | disclosed |
| EP-0625161-B1 | PROCESS FOR RECOVERING A HIGH-PURITY VIRUS-INACTIVATED FACTOR VIII/VON WILLEBRAND FACTOR COMPLEX BY ANION EXCHANGER CHROMATOGRAPHY | OCTAPHARMA AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| CN-1212018-A | Method for producing alpha-hydroxy acid using microorganism, and novel microorganism | NIPPON SODA CO (JP) | 1999-03-24 | — | — | CN | disclosed |
| US-5714590-A | Process for recovering a high-purity virus-inactivated factor VIII by anion exchanger chromatography | OCTAPHARMA AG (CH) | 1998-02-03 | — | — | US | disclosed |
| EP-0625161-A1 | PROCESS FOR RECOVERING A HIGH-PURITY VIRUS-INACTIVATED FACTOR VIII BY ANION EXCHANGER CHROMATOGRAPHY | OCTAPHARMA AG (CH) | 1994-11-23 | — | — | EP | disclosed |
| CN-1023298-C | Isolated material | MERCK PATENT GMBH (DE) | 1993-12-29 | — | — | CN | disclosed |
| WO-1993015105-A1 | PROCESS FOR RECOVERING A HIGH-PURITY VIRUS-INACTIVATED FACTOR VIII BY ANION EXCHANGER CHROMATOGRAPHY | OCTAPHARMA AG (CH) | 1993-08-05 | — | — | WO | disclosed |
| CN-1036516-A | Parting material | MERCK PATENT GMBH (DE) | 1989-10-25 | — | — | CN | disclosed |