Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 7/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.44 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628089 | 0.84 | PIK3CA (0.40) | MAPTCYP1A2CYP2D6MTORPIK3CA | |
| SCHEMBL30364648 | 0.83 | MTOR (0.47) | MTORPIK3CAMAP3K12RICTORRPTOR | |
| SCHEMBL20692825 | 0.83 | MTOR (0.47) | MTORPIK3CAMAP3K12RICTORRPTOR | |
| SCHEMBL628557 | 0.81 | PIK3CA (0.39) | MAPTCYP1A2CYP2D6MTORPIK3CA | |
| SCHEMBL629594 | 0.73 | MTOR (0.40) | MTORPIK3CAMAP3K12SMN1; SMN2RICTOR | |
| SCHEMBL9607534 | 0.71 | MTOR (0.38) | MTORPIK3CAMAP3K12PIK3CDPIK3CB | |
| SCHEMBL21262121 | 0.71 | MTOR (0.43) | MTORPIK3CAMAP3K12RICTORRPTOR | |
| SCHEMBL30137169 | 0.71 | MTOR (0.43) | MTORPIK3CAMAP3K12RICTORRPTOR | |
| SCHEMBL23436359 | 0.70 | MTOR (0.36) | MTORPIK3CAMAP3K12PIK3CDPIK3R1 | |
| SCHEMBL20693010 | 0.70 | CYP1A2 (0.54) | MAPTCYP1A2CYP2D6MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120854-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010120854-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-10-21 | — | — | WO | disclosed |