Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725716 | 1.00 | MAPT (0.59) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL9814258 | 0.89 | HDAC3 (0.56) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL29110388 | 0.89 | HPGD (0.61) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL9814260 | 0.89 | HDAC3 (0.56) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL1975200 | 0.83 | MAPT (0.63) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL14482921 | 0.83 | MAPT (0.63) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL1975201 | 0.83 | MAPT (0.63) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL14482127 | 0.78 | MAPT (0.45) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL14482124 | 0.78 | MAPT (0.45) | MAPTGAAKDM4EKMT2ATDP1 | |
| SCHEMBL10491011 | 0.77 | MAPT (0.65) | MAPTGAAKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070232-A1 | NOVEL RARE EARTH ELEMENT CRYPTATES INCLUDING A TETRAAZATRIPHENYLENE UNIT | CIS BIO INTERNATIONAL (FR) | 2010-06-24 | — | — | WO | disclosed |