Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720859 | 0.92 | PARP10 (0.46) | PARP10PARP15PDK2 | |
| SCHEMBL2206445 | 0.88 | PARP10 (0.51) | PARP10PARP15MAOAMAOBPDK2 | |
| SCHEMBL18617050 | 0.83 | PARP10 (0.53) | PARP10PARP15MAOAMAOB | |
| SCHEMBL3721180 | 0.81 | PARP10 (0.50) | PARP10PARP15MAOAMAOBPDK2 | |
| SCHEMBL14858182 | 0.81 | PARP10 (0.50) | PARP10PARP15MAOAMAOB | |
| SCHEMBL21694070 | 0.81 | PARP10 (0.51) | PARP10PARP15MAOAMAOB | |
| SCHEMBL3721537 | 0.81 | PARP10 (0.51) | PARP10PARP15MAOAMAOBPDK2 | |
| SCHEMBL25901096 | 0.81 | PARP10 (0.64) | PARP10PARP15MAOAMAOBPDK2 | |
| SCHEMBL24266751 | 0.79 | PARP10 (0.48) | PARP10PARP15MAOAMAOB | |
| SCHEMBL9559103 | 0.79 | CHEK1 (0.41) | PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |