Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736827 | 0.89 | KMT2A (0.51) | OPRL1 | |
| SCHEMBL3747001 | 0.85 | OPRL1 (0.65) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3742290 | 0.84 | OPRL1 (0.69) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3727227 | 0.84 | OPRL1 (0.70) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3737039 | 0.83 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3731861 | 0.81 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3729432 | 0.81 | OPRL1 (0.71) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3735016 | 0.80 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3728624 | 0.80 | OPRL1 (0.68) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3733538 | 0.78 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | OPRL1 233/4885OPRM1 610/4885OPRK1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.