Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.49 |
| ▸ | ACACA | Q13085 | 11/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727054 | 0.90 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL3720735 | 0.88 | ACACB (0.48) | ACACBACACAALOX5MMP9 | |
| Hydrochloric Acid SCHEMBL3722698 | 0.87 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL3720740 | 0.87 | ACACB (0.47) | ACACBACACAALOX5 | |
| SCHEMBL3722662 | 0.87 | ACACB (0.47) | ACACBACACAALOX5 | |
| SCHEMBL3720867 | 0.87 | ACACB (0.49) | ACACBACACA | |
| SCHEMBL13076469 | 0.84 | ACACB (0.45) | ACACBACACAALOX5 | |
| SCHEMBL13076378 | 0.83 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL13076818 | 0.83 | ACACB (0.43) | ACACBACACAALOX5 | |
| SCHEMBL3727673 | 0.81 | ACACB (0.48) | ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |