Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227025 | 1.00 | NR4A1 (0.50) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL9914141 | 0.85 | NR4A1 (0.46) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL25378960 | 0.85 | NR4A1 (0.46) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL25378954 | 0.85 | NR4A1 (0.46) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL8722415 | 0.82 | NR4A1 (0.50) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL18396248 | 0.81 | NR4A1 (0.42) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL18396247 | 0.81 | NR4A1 (0.42) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL9914143 | 0.79 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL10319210 | 0.79 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL9915224 | 0.79 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637550-B1 | Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby | UNIV CARNEGIE MELLON (US) | 2017-09-20 | — | — | EP | disclosed |
| US-7825199-B1 | mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft | CARNEGIE MELLON UNIVERSITY (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1637550-A2 | Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby | CARNEGIE-MELLON UNIVERSITY (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1171496-B1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | UNIV CARNEGIE MELLON (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20040171779-A1 | Redox systems; using transition metal complex catalysts; atom transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (A NON-PROFIT PENNSYLVANIA ORGANIZATION) | 2004-09-02 | — | — | US | disclosed |
| EP-1171496-A1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | CARNEGIE-MELLON UNIVERSITY (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000056795-A1 | CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY | CARNEGIE MELLON UNIVERSITY (US) | 2000-09-28 | — | — | WO | disclosed |
| EP-0008323-B1 | PROCESS FOR THE PREPARATION OF PYRIDINE ALDEHYDES AND THEIR DERIVATIVES, AND COMPOUNDS MADE BY THIS PROCESS | CIBA-GEIGY AG (CH) | 1982-08-25 | — | — | EP | disclosed |
| US-4322536-A | Process for producing pyridinaldehydes | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4237275-A | Process for producing hydrazone derivatives of pyridinaldehydes | CIBA-GEIGY CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0008323-A1 | Process for the preparation of pyridine aldehydes and their derivatives, and compounds made by this process | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |