SCHEMBL3731925

SCHEMBL3731925

[CH2]C1CC(F)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1867100 0.75
SCHEMBL7363257 0.74
SCHEMBL24425399 0.71
SCHEMBL726015 0.71
SCHEMBL4660677 0.71
SCHEMBL8051471 0.70
SCHEMBL8051252 0.70
SCHEMBL423353 0.64
SCHEMBL135033 0.64
SCHEMBL4574321 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130149281-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2013-06-13 US claimed
US-8445527-B2 Organic compounds and their uses NOVARTIS AG (CH) 2013-05-21 US claimed
EP-2518079-A2 HCV/HIV inhibitors and their uses Novartis AG (CH) 2012-10-31 EP claimed
US-20120231998-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2012-09-13 US claimed
US-8211932-B2 Organic compounds and their uses NOVARTIS AG (CH) 2012-07-03 US claimed
US-20100331243-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2010-12-30 US claimed
US-7825152-B2 serine protease inhibitors, for the treatment of hepatitis c virus infections NOVARTIS AG (CH) 2010-11-02 US claimed
EP-2007789-A2 HCV/HIV INHIBITORS AND THEIR USES Novartis Pharma AG (CH) 2008-12-31 EP claimed
US-20070286842-A1 Organic Compounds and Their Uses NOVARTIS AG (CH) 2007-12-13 US claimed
WO-2007133865-A2 HCV/HIV INHIBITORS AN THEIR USES NOVARTIS AG (CH) 2007-11-22 WO claimed