Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7541149 | 0.97 | CES1 (0.42) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL28279262 | 0.97 | CES1 (0.42) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL21836054 | 0.97 | CA1 (0.48) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL28521370 | 0.97 | CES1 (0.42) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL2139863 | 0.97 | CA1 (0.48) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL17491792 | 0.97 | CES1 (0.42) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL31411090 | 0.97 | CA1 (0.48) | CES1CA1CES2FFAR3HDAC3 | |
| Butanedione SCHEMBL21839440 | 0.95 | CES1 (0.46) | CES1CA1CES2FFAR3HDAC3 | |
| Acetic Acid SCHEMBL28184776 | 0.93 | CES1 (0.39) | CES1CA1CES2FFAR3HDAC3 | |
| Bicarbonate SCHEMBL27704869 | 0.92 | CA1 (0.46) | CES1CA1CES2FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 12776 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080612-A | Acrylic acid in-situ polymerized silane modified polyether hybrid resin, application, waterproof coating and preparation method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080837-A | Adhesive for repairing photovoltaic module, preparation method and repairing method of photovoltaic module | — | 2026-05-26 | — | — | CN | claimed |
| CN-116144183-B | High-temperature vulcanized silicone rubber and preparation method thereof | SHANDONG UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-120441751-B | Concrete waterproofing agent and preparation method thereof | NANJING TECH UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119859238-B | Bio-based chain extender and application thereof | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119592294-B | Quick-curing bi-component condensation dealcoholized silicone adhesive and preparation method thereof | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037137-A | Organosilicon modified polyurethane acrylic ester, and preparation method and application thereof | 合肥中聚和成光电材料股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037817-A | Pre-laid waterproof coiled material and preparation method and application method thereof | 北京东方雨虹防水技术股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122011613-A | Multidimensional reinforced silane crosslinked chlorosulfonated polyethylene nanocomposite and preparation method and application thereof | 唐山华通特种线缆制造有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-116836678-B | Salt spray corrosion resistant double-component silicone structural adhesive and preparation method thereof | 杭州之江有机硅化工有限公司 | 2026-05-12 | — | — | CN | claimed |
| WO-1981003291-A1 | METHOD OF PROVIDING WATERPROOF COATING FOR MASONRY WALLS | DOW CORNING (US) | 1981-11-26 | — | — | WO | claimed |
| EP-0040459-A1 | Method of providing waterproof coating for masonry walls | DOW CORNING CORPORATION (US) | 1981-11-25 | — | — | EP | claimed |
| US-4293616-A | CELLULOSE, MASONRY, CURING | GENERAL ELECTRIC COMPANY (US) | 1981-10-06 | — | — | US | claimed |
| US-4273813-A | CURABLE EMULSION OF HYDROXYL ENDBLOCKED POLYDIORGANOSILOXANE, AMORPHOUS SILICA, AND AN ORGANIC TIN SALT | DOW CORNING CORPORATION (US) | 1981-06-16 | — | — | US | claimed |
| US-4265792-A | Compositions including mercaptoorganopolysiloxanes and stannic salts of carboxylic acids | DOW CORNING CORPORATION (US) | 1981-05-05 | — | — | US | claimed |
| US-4257932-A | CHAIN STOPPED POLYSILOXANE, FLUID POLYSILOXANE-SILICATE AND A CROSSLINKING AGENT; MOISTURE CURABLE TO FORM GASKETS | GENERAL ELECTRIC COMPANY (US) | 1981-03-24 | — | — | US | claimed |
| EP-0000879-B1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBONIC ACID ESTERS | BAYER AG (DE) | 1980-08-20 | — | — | EP | claimed |
| EP-0000879-A1 | Process for the preparation of aromatic carbonic acid esters | BAYER AG (DE) | 1979-03-07 | — | — | EP | claimed |
| US-4115356-A | EPOXYTRIALKOXYSILANES | DOW CORNING CORPORATION (US) | 1978-09-19 | — | — | US | claimed |
| US-3957714-A | Method for making paintable silicone surfaces and elastomer | DOW CORNING CORPORATION (US) | 1976-05-18 | — | — | US | claimed |