Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811761 | 0.87 | TARBP2 (0.51) | TARBP2RAB9AKDM4ESMN1; SMN2DGAT1 | |
| SCHEMBL596762 | 0.84 | TARBP2 (0.52) | TARBP2RAB9AKDM4ESMN1; SMN2DGAT1 | |
| SCHEMBL6602803 | 0.83 | TARBP2 (0.52) | TARBP2SMN1; SMN2DGAT1TSHRPOLB | |
| SCHEMBL3611262 | 0.78 | IKBKB (0.50) | TARBP2RAB9AKDM4ESMN1; SMN2IKBKB | |
| SCHEMBL11620466 | 0.75 | IKBKB (0.54) | TARBP2RAB9AKDM4EIKBKBALDH1A1 | |
| SCHEMBL13685150 | 0.73 | TARBP2 (0.53) | TARBP2RAB9AKDM4ESMN1; SMN2PDCD4 | |
| SCHEMBL2789114 | 0.72 | TARBP2 (0.50) | TARBP2RAB9AKDM4ESMN1; SMN2DGAT1 | |
| SCHEMBL4970219 | 0.72 | IKBKB (0.53) | RAB9AKDM4ESMN1; SMN2IKBKBALDH1A1 | |
| SCHEMBL10265150 | 0.72 | MAPK1 (0.46) | TARBP2KDM4ESMN1; SMN2IKBKBALDH1A1 | |
| SCHEMBL2490988 | 0.72 | TARBP2 (0.59) | TARBP2RAB9AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170875-A1 | AMINOALKYLAZOLE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | Wyeth LLC (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009012252-A1 | AMINOALKYLAZOLE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |