⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477190 | 1.00 | — | — | |
| SCHEMBL891810 | 1.00 | — | — | |
| Ethylene Glycol SCHEMBL8768679 | 0.89 | TSHR (0.32) | — | |
| SCHEMBL2388236 | 0.89 | — | — | |
| SCHEMBL29652095 | 0.84 | HSD17B10 (0.31) | — | |
| SCHEMBL19859739 | 0.84 | HSD17B10 (0.31) | — | |
| SCHEMBL6722145 | 0.83 | — | — | |
| SCHEMBL10416346 | 0.83 | CA1 (0.30) | — | |
| SCHEMBL1475674 | 0.83 | — | — | |
| SCHEMBL891970 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | claimed |
| US-20060210528-A1 | Therapy for tropical diseases | ASPIRE BIOTECH, INC. | 2006-09-21 | — | — | US | claimed |
| US-20030143189-A1 | Therapy for topical diseases | ASPIRE BIOTECH, INC. | 2003-07-31 | — | — | US | claimed |
| WO-2003041686-A2 | IMPROVED THERAPY FOR TOPICAL DISEASES | MEDLOGIC GLOBAL LIMITED (GB) | 2003-05-22 | — | — | WO | claimed |
| US-6514977-B1 | For treating p38 kinase mediated disorders | G.D. SEARLE & COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6423713-B1 | Substituted pyrazoles as p38 kinase inhibitors | G. D. SEARLE & COMPANY | 2002-07-23 | — | — | US | claimed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | claimed |
| EP-0286230-B1 | PLUG LID FOR A CONTAINER | CMB Foodcan plc (GB) | 1991-09-11 | — | — | EP | claimed |
| CN-112513219-B | Photosensitive resin composition, cured film, laminate, method for producing cured film, and semiconductor device | 富士胶片株式会社 | 2023-10-20 | — | — | CN | disclosed |
| EP-3529304-B1 | METHOD FOR PRODUCING A FOAM BODY HAVING AN INTERNAL STRUCTURE | COVESTRO DEUTSCHLAND AG (DE) | 2020-12-23 | — | — | EP | disclosed |
| EP-2922887-B1 | PROCESS FOR THE PREPARATION OF PUR FLEXIBLE FOAMS | COVESTRO DEUTSCHLAND AG (DE) | 2020-03-11 | — | — | EP | disclosed |
| EP-3529304-A1 | METHOD FOR PRODUCING A FOAM BODY HAVING AN INTERNAL STRUCTURE | Covestro Deutschland AG (DE) | 2019-08-28 | — | — | EP | disclosed |
| WO-2018072891-A1 | METHOD FOR PRODUCING A FOAM BODY HAVING AN INTERNAL STRUCTURE | COVESTRO DEUTSCHLAND AG (DE) | 2018-04-26 | — | — | WO | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5681867-A | INTRODUCING FLAKED GLASS REINFORCING FILLER INTO HYDROXY FUNCTIONAL TERTIARY AMINE POLYOXYALKYLENE POLYETHER POLYOL COMPOSITION PRIOR TO REACTION WITH ISOCYANATE | BASF CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| EP-0742211-A1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-4222931-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant | ARGUS CHEMICAL CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4210577-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol | ARGUS CHEMICAL CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |