SCHEMBL3733671

SCHEMBL3733671

O=[N+](O)c1ccc(OP(=O)([O-])O)cc1.[NaH]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
THRB P10828 1/20 0.38
SRC P12931 1/20 0.35
TSHR P16473 1/20 0.35
AKR1C3 P42330 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35321 0.98 CA1 (0.55) CA1CA2CES2CES1BCHE
SCHEMBL11322611 0.96 CA1 (0.53) CA1CA2CES2CES1BCHE
SCHEMBL1024521 0.81 CA1 (0.49) CA1CA2CES2CES1BCHE
P-Nitrophenylphosphate SCHEMBL6681723 0.81 CA1 (0.73) CA1CA2CES2CES1BCHE
SCHEMBL4918240 0.81 CA1 (0.53) CA1CA2CES2CES1BCHE
SCHEMBL11521309 0.79 CA1 (0.44) CA1CA2CES2CES1BCHE
SCHEMBL867575 0.79 CA1 (0.64) CA1CA2CES2CES1BCHE
SCHEMBL5487192 0.77 SRC (0.39) CA1CA2CES2CES1ALDH1A1
SCHEMBL11588710 0.77 CA1 (0.62) CA1CA2CES2CES1BCHE
Water SCHEMBL9045485 0.77 CA1 (0.62) CA1CA2CES2CES1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106754817-B Expression method of recombinant autotaxin 山西省生物研究院有限公司 2021-02-05 CN claimed
CN-106754817-A A kind of expression for recombinating autocrine motility factor 山西省生物研究所 2017-05-31 CN claimed
CN-102297962-A Kit for detecting alkaline phosphatase 2011-12-28 CN claimed
CN-111596051-B Method for acquiring information of measured substance and method for capturing measured substance 希森美康株式会社 2025-05-16 CN disclosed
CN-118718951-A Paranitrophosphate disodium production system 深圳瑞亚力集团有限公司 2024-10-01 CN disclosed
CN-115786166-B Klebsiella pneumoniae and application thereof 湖南农业大学 2023-12-01 CN disclosed
EP-3341112-B1 METHODS AND COMPOSITIONS FOR PROTEIN PURIFICATION AND ENZYME REACTION UNIV CALIFORNIA (US) 2023-11-08 EP disclosed
CN-113552107-B Application of cellulose-based carbon quantum dots in organophosphorus pesticide detection 齐鲁工业大学 2023-05-26 CN disclosed
CN-115011337-B Boric acid functionalized carbon dot and preparation method and application thereof 齐鲁工业大学 2023-05-05 CN disclosed
CN-115093978-A Tobacco endophytic fungus secreting resveratrol and application thereof in biological control 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2022-09-23 CN disclosed
CN-108998432-B Acid phosphatase gene and application 中国农业科学院农业资源与农业区划研究所 2022-04-12 CN disclosed
EP-0061731-B2 NOVEL PHOSPHORIC ESTER AND A METHOD FOR QUANTITATIVE ANALYSIS OF AN ALKALINE PHOSPHATASE USING THE SAME AS A SUBSTRATE Fuji Photo Film Co., Ltd. (JP) 1992-01-29 EP disclosed
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP disclosed
US-4797476-A Mono-4-arylazoaryl phosphoric esters FUJI SHASHIN FILM KABUSHIKI KAISHA (JP) 1989-01-10 US disclosed
EP-0269979-A2 Analytical element for measuring alkaline phosphatase KONICA CORPORATION (JP) 1988-06-08 EP disclosed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP disclosed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO disclosed
EP-0061731-B1 NOVEL PHOSPHORIC ESTER AND A METHOD FOR QUANTITATIVE ANALYSIS OF AN ALKALINE PHOSPHATASE USING THE SAME AS A SUBSTRATE Fuji Photo Film Co., Ltd. (JP) 1986-10-29 EP disclosed
US-4610960-A Monoclonal antibody to thrombospondin and method for assaying for and isolating thrombospondin WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1986-09-09 US disclosed
EP-0061731-A2 Novel phosphoric ester and a method for quantitative analysis of an alkaline phosphatase using the same as a substrate Fuji Photo Film Co., Ltd. (JP) 1982-10-06 EP disclosed