Triethylene Glycol

Triethylene Glycol

SCHEMBL3733987

CCCCOC(C(=O)O)C(O)C(=O)O.OCCOCCOCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
CYP3A4 P08684 2/20 0.35
RARB P10826 2/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLCO1B3 Q9NPD5 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
HCAR2 Q8TDS4 1/20 0.33
ATM Q13315 1/20 0.33
ACHE P22303 1/20 0.33
GPR84 Q9NQS5 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL3729115 1.00 TSHR (0.48) TSHRMEN1KMT2ATHRBHTT
Di(Hydroxyethyl)Ether SCHEMBL3742226 0.98 TSHR (0.50) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL3732641 0.90 ATM (0.37) TSHRALDH1A1MAPK1HCAR2ATM
SCHEMBL3739748 0.89 TSHR (0.43) TSHRMEN1KMT2ATHRBHTT
SCHEMBL3728703 0.89 TSHR (0.43) TSHRMEN1KMT2ATHRBHTT
1,4-Butanediol SCHEMBL3743070 0.89 SMN1; SMN2 (0.37) TSHRMEN1KMT2AALDH1A1LMNA
Di(Hydroxyethyl)Ether SCHEMBL3730840 0.89 TSHR (0.39) TSHRMEN1KMT2ATHRBHTT
SCHEMBL2979038 0.88 ATM (0.41) TSHRALDH1A1MAPK1HCAR2ATM
SCHEMBL27720867 0.87 ATM (0.39) TSHRALDH1A1MAPK1HCAR2ATM
Propylene Glycol SCHEMBL3731844 0.84 ATM (0.35) TSHRMAPTALDH1A1HCAR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed